Abstract: The Scholix Framework (SCHOlarly LInk eXchange) is a high level interoperability framework for exchanging information about the links between scholarly literature and data, as well as between datasets. Over the past decade, publishers, data centers, and indexing services have agreed on and implemented numerous bilateral agreements to establish bidirectional links between research data and the scholarly literature. However, because of the considerable differences inherent to these many agreements, there is very limited interoperability between the various solutions. This situation is fueling systemic inefficiencies and limiting the value of these, separated, sets of links. Scholix, a framework proposed by the RDA/WDS Publishing Data Services working group, envisions a universal interlinking service and proposes the technical guidelines of a multi-hub interoperability framework. Hubs are natural collection and aggregation points for data-literature information from their respective communities. Relevant hubs for the communities of data centers, repositories, and journals include DataCite, OpenAIRE, and Crossref, respectively. The framework respects existing community-specific practices while enabling interoperability among the hubs through a common conceptual model, an information model and open exchange protocols. The proposed framework will make research data, and the related literature, easier to find and easier to interpret and reuse, and will provide additional incentives for researchers to share their data.